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Dogwood Executes 25-for-1 Reverse Split, Secures $19.5M for Phase 2b Halneuron Trial

NASDAQ

DWTX

September 29, 2025 | 1:23pm
DOGWOOD THERAPEUTICS INC
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As of September 29, 2025 1:23pm

Dogwood Therapeutics Inc (NASDAQ: DWTX)

Dogwood Therapeutics Inc, headquartered in Alpharetta, Georgia, is a development-stage biotechnology company founded in 2020. The company specializes in therapeutics for pain and fatigue illnesses. Its lead candidate, Halneuron®, is a highly selective sodium channel blocker aimed at treating moderate-to-severe chemotherapy-induced neuropathic pain (CINP) and other pain indications. Additionally, Dogwood is advancing two antiviral combination therapies—IMC-1 and IMC-2—to address conditions associated with immune responses triggered by viral infections, including Long-COVID and fibromyalgia.

Corporate Structure and Experience

Dogwood employs between 11 and 50 professionals across various functions, including research and development, clinical operations, regulatory affairs, and corporate roles. Following the 25-for-1 reverse stock split on October 9, 2024, the company began trading under the ticker DWTX. The leadership team includes:

  • Greg Duncan, Chief Executive Officer
  • Mike Gendreau, Chief Medical Officer
  • Angela Walsh, Chief Financial Officer
  • Meng Zhou, Vice President of Manufacturing

The board of directors comprises experienced professionals such as Rick Keefer, John Thomas, and Abel De La Rosa, who bring backgrounds in drug development, finance, and strategic partnerships.

Biotechnology

Biotechnology by Sangharsh Lohakare

Developments and News

On October 2, 2024, Virios Therapeutics and Wex Pharmaceuticals completed a share exchange agreement to form Dogwood Therapeutics, Inc. Concurrently, the company secured $19.5 million in committed debt financing from an affiliate of CK Life Sciences. The funding consisted of $16.5 million at closing, with an additional $3 million scheduled for the first quarter of 2025. The 25-for-1 reverse stock split took effect on October 9, 2024, coinciding with the commencement of trading on the Nasdaq Capital Market.

Planned clinical milestones include:

  • Halneuron Phase 2b interim readout expected in the second half of 2025.
  • IMC-2 Phase 2 top-line results anticipated in early fourth quarter of 2024.
  • IMC-1 is prepared for Phase 3 development for fibromyalgia and has received FDA Fast Track Designation.

As of September 29, 2025, the stock price was $8.27, reflecting a 49.82% increase with a volume of 8,051,082 shares traded.

Financial and Strategic Analysis

Dogwood has not yet generated revenue, relying on equity and debt financing for its operations. The $19.5 million debt facility is designated to support ongoing clinical trials and research activities through key data readouts. On a fully diluted basis, the combined entity's equity value was estimated at approximately $105 million at closing, excluding transaction costs. Continued progress in Halneuron's Phase 2b trial and favorable top-line data from IMC-2 will be critical for potential licensing agreements or further fundraising. Key challenges include the outcomes of clinical trials, regulatory approval processes, and the necessity for additional capital to further develop the product pipeline.

Market Position and Industry Context

In the biotechnology sector, Dogwood addresses unmet needs in non-opioid pain management and conditions resulting from viral infections. Halneuron operates through the Nav1.7 sodium channel mechanism and distinguishes itself by demonstrating an absence of tolerance build-up, addiction potential, or euphoria in over 700 clinical trial participants. The IMC-1 and IMC-2 therapies utilize combinations of valacyclovir or famciclovir with celecoxib to target Long-COVID and fibromyalgia—conditions that currently have limited treatment options. Competition encompasses both large pharmaceutical companies and emerging biotechnologies, highlighting the importance of demonstrating effective clinical results for market penetration.

tl;dr

On October 2, 2024, Dogwood was formed from the merger of Virios and Wex. A 25-for-1 reverse split occurred on October 9, 2024. The company raised $19.5 million in debt financing to support its pipeline. As of September 29, 2025, DWTX traded at $8.27 (+49.82%). Upcoming milestones include the Halneuron Phase 2b interim analysis in late 2025 and IMC-2 Phase 2 data in early Q4 2024. Positive results may lead to licensing agreements or additional capital raises.

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